The Importance of Methyl Groups
Did you ever wonder WHY all of a sudden someone develops a neurodegenerative disorder, heart disease, an autoimmune condition or even…cancer? Did it just drop down out of the sky and land on their head? No! They expressed a “bad gene!” How do you express “bad genes” like autoimmune, MS, ALS, Parkinson’s, heart disease or cancer? The answer is depleted methyl groups! Depletion of your body’s methyl groups is how “bad genes” are expressed.
How are methyl groups in our body depleted? By consuming a poor diet loaded with “white death” – white sugar, white flour and white salt, “bad oils” – trans-fatty acids and hydrogenated oils, produce loaded with pesticides and herbicides, junk food, drinks loaded with caffeine, high fructose corn syrup and acid, genetically-modified foods, and stress!
What helps create methyl groups? HCL or stomach acid! This is WHY it is vital for everyone to have the proper amount of stomach acid (HCL)
We create massive amounts of HCL when we are young but as we age, we make less and less. Again, further decreases in stomach acid or HCL are caused by excess stress and a poor diet. Methyl groups are VITAL for normal cell replication at the level of the DNA! They literally turn genes “on” or “off.”
When you have depleted methyl groups, bad genes like cancer causing oncogenes are turned “on” and good genes like cancer preventing tumor-suppressor genes are turned “off.” When you have sufficient methyl groups, good genes, like tumor-suppressor genes, are turned “on” and bad genes like oncogenes are turned “off.”
Methyl groups are also vital for phase II liver detoxification, protein methylation, homocysteine metabolism (increasing the methyl group decreases inflammation), neurotransmitter synthesis and nucleic acid synthesis.
Inadequate methylation capacity can lead to birth defects, depression, cognitive decline, diseases and cancer. Impaired methylation has even been associated with autism.
So… a patient has depleted methyl groups and all of a sudden they come in contact with a toxin, prolonged exposure to EMFs, a dental infection, or severe emotional stress and… BOOM… they express the bad gene. The next thing you know, they have a neurodegenerative disorder like Parkinson’s, ALS, Alzheimer’s, an autoimmune condition or cancer. None of these conditions drop out of the sky and land on a patient; there has to be a cause and the cause is depleted methyl groups.
How do you test for adequate levels of HCL? By checking the patient’s blood work and looking at the total protein, serum globulin, BUN and phosphorous. If some or all are abnormal, you most likely have lower levels of HCL. How do you test for methyl groups? There is a specific urine test that you can run called the Basic Organic Acid test.
How do you increase HCL? The only way to increase HCL is by using supplements. Using supplements to increase HCL in the stomach is one of THE BEST means of preventing serious illness! Many patients cannot tolerate HCL directly in the beginnings because their stomach acid is so low so I use a product from Premier Research Labs (PRL) called Gastroven as a tea (2-3 capsules in hot water). I eventually move them up to PRL’s HCL, HCL Activator and Digest (pancreatic enzymes) after every meal. Taking HCL/HCL Activator after every meal is something that should be done by everyone over the age of 25. Up until the age of 25, using pink salt will suffice. Throw that blue container of white garbage salt in the trash! Pink Salt if not chemically processed like white salt and it contains calcium, magnesium and other trace minerals. The body will take the chloride molecule from the pink salt (NaCl) and make HCL. No matter what age, using pink salt is one of the best things that you can do to improve your health!
Please note that HCL breaks down food BUT by itself HCL cannot methylate a cell. HCL Activator provides a buffer in the form of potassium. Potassium added to HCL creates tri-methyl glycine and it is the tri-methyl glycine that adds three (3) methyl (CH3) groups to each cell.
Methyl (CH3) is part of an acetyl group (COCH3) in chemistry. Again, deacteylation occurs in cancer. It was Dr. Stanislaw Burzynski that first showed that deacteylation “turns on” oncogenes and “turns off” tumor suppressor cells. Acetylation occurs when we add the methyl (CH3) group to the chemistry mixture and acetylation “turns off” oncogenes and “turns on” tumor suppressor cells.
As a side note, patients that wake up in the middle of the night and are unable to fall back to sleep usually have a problem with their stomach. They suffer from hypochlorhydria or low HCL. Patients that have difficulty falling asleep at night usually suffer from a gall bladder problem and feeling groggy in the morning is usually an adrenal issue.
Read more about autoimmunity in this month’s “The Wellness Connection”.